About Polifeprosan 20 / Carmustine
Class: | Antineoplastic agent, alkylating agent
Use: | Treatment of recurrent glioblastoma multiforme as an adjunct to surgery and radiation therapy
Adult dose: | One wafer (7.7 mg) implanted into the resection cavity at the time of surgery; may be used in combination with other therapies
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Common side effects include nausea, vomiting, headache, seizures, and local reactions at the implant
Drug Class
Antineoplastic agent, alkylating agent
Uses & Indications
Treatment of recurrent glioblastoma multiforme as an adjunct to surgery and radiation therapy
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Eisai LTD, UNITED KINGDOM
Package Size
8s
Price & Supplier
Price in UAE: AED 46749.00
Dosage Information
Adult Dose
One wafer (7.7 mg) implanted into the resection cavity at the time of surgery; may be used in combination with other therapies
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Common side effects include nausea, vomiting, headache, seizures, and local reactions at the implantation site
Contraindications & Precautions
Hypersensitivity to carmustine or any component of the formulation; pregnancy and breastfeeding
Important Warnings
Risk of severe pulmonary toxicity; monitor lung function; potential for myelosuppression; use caution in patients with pre-existing lung disease or those receiving other myelosuppressive agents
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.