About Polifeprosan 20 / Carmustine
            
            Class: | Antineoplastic agent, alkylating agent  
Use: | Treatment of recurrent glioblastoma multiforme as an adjunct to surgery and radiation therapy  
Adult dose: | One wafer (7.7 mg) implanted into the resection cavity at the time of surgery; may be used in conjunction with radiation therapy  
Pediatric dose: | Safety and efficacy not established in pediatric patients  
Side effects: | Common side effects include nausea, vomiting, headache, seizures, and local site reactions (e.g., edema, inf
         
        
            
                
                
                    
                        Drug Class
                    
                    Antineoplastic agent, alkylating agent
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of recurrent glioblastoma multiforme as an adjunct to surgery and radiation therapy
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Arbor Pharmaceuticals, United States of America
                    
                    
                    Package Size
                    8's
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 161519.20
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        One wafer (7.7 mg) implanted into the resection cavity at the time of surgery; may be used in conjunction with radiation therapy
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Common side effects include nausea, vomiting, headache, seizures, and local site reactions (e.g., edema, infection)
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to carmustine or any component of the wafer; pregnancy; breastfeeding
         
        
        
            
                Important Warnings
            
            Risk of severe pulmonary toxicity; monitor for signs of lung toxicity; may cause myelosuppression; use caution in patients with impaired liver or kidney function; potential for secondary malignancies
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.