About Guselkumab
            
            Class: | Interleukin-23 (IL-23) inhibitor  
Use: | Treatment of moderate to severe plaque psoriasis in adults, active psoriatic arthritis, and active ankylosing spondylitis  
Adult dose: | Initial dose: 100 mg subcutaneously at week 0 and week 4, followed by maintenance dose of 100 mg every 8 weeks  
Pediatric dose: | Safety and efficacy not established in pediatric patients under 18 years of age  
Side effects: | Upper respiratory infections, injection site reactions, headache, fatigue, and nau
         
        
            
                
                
                    
                        Drug Class
                    
                    Interleukin-23 (IL-23) inhibitor
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of moderate to severe plaque psoriasis in adults, active psoriatic arthritis, and active ankylosing spondylitis
                 
                
                
                    
                        Storage Requirements
                    
                    Store in the refrigerator (2°C to 8°C or 36°F to 46°F); may be stored at room temperature (up to 25°C or 77°F) for up to 21 days; do not freeze
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Janssen Cilag International N.V.  [Beerse;BELGIUM], Belgium
                    
                    
                    Package Size
                    1 Pre-filled Pen (2 mL)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 23123.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Initial dose: 100 mg subcutaneously at week 0 and week 4, followed by maintenance dose of 100 mg every 8 weeks
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients under 18 years of age
                    
                 
                
                
                    
                        Side Effects
                    
                    Upper respiratory infections, injection site reactions, headache, fatigue, and nausea
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to guselkumab or any component of the formulation; active infections, including tuberculosis
         
        
        
            
                Important Warnings
            
            Risk of serious infections; monitor for signs and symptoms of infection; may increase risk of malignancies; live vaccines should be avoided during treatment
         
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.