About Irinotecan Hydrochloride
Class: | Antineoplastic agent, Topoisomerase I inhibitor
Use: | Treatment of metastatic colorectal cancer, often in combination with other chemotherapy agents; also used in the treatment of small cell lung cancer.
Adult dose: | Initial dose is typically 125 mg/m² administered as an intravenous infusion over 90 minutes every 21 days; dosage may be adjusted based on patient tolerance and side effects.
Pediatric dose: | Safety and efficacy have not been established in pediatric patients; use
Drug Class
Antineoplastic agent, Topoisomerase I inhibitor
Uses & Indications
Treatment of metastatic colorectal cancer, often in combination with other chemotherapy agents; also used in the treatment of small cell lung cancer.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze.
Manufacturer & Packaging
Manufacturer: Jiangsu Hengrui Pharmaceuticals Co. Ltd., China
Package Size
1 x 5 ml Glass vial
Price & Supplier
Price in UAE: AED 324.00
Dosage Information
Adult Dose
Initial dose is typically 125 mg/m² administered as an intravenous infusion over 90 minutes every 21 days; dosage may be adjusted based on patient tolerance and side effects.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; use is generally not recommended unless in a clinical trial setting.
Side Effects
Common side effects include diarrhea, nausea, vomiting, abdominal pain, fatigue, neutropenia, and alopecia.
Contraindications & Precautions
Hypersensitivity to irinotecan or any component of the formulation; severe bone marrow suppression; patients with a history of severe diarrhea or bowel obstruction.
Important Warnings
Risk of severe diarrhea, which can be life-threatening; monitor for signs of dehydration; may cause myelosuppression leading to increased risk of infection; caution in patients with liver impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.