About Tolvaptan
Class: | Vasopressin receptor antagonist
Use: | Treatment of autosomal dominant polycystic kidney disease (ADPKD) to slow the progression of kidney function decline
Adult dose: | Initial dose of 60 mg once daily; may be increased to 90 mg once daily based on tolerability and clinical response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Common side effects include thirst, dry mouth, increased urination, and potential liver enzyme elevations
Drug Class
Vasopressin receptor antagonist
Uses & Indications
Treatment of autosomal dominant polycystic kidney disease (ADPKD) to slow the progression of kidney function decline
Storage Requirements
Store at room temperature, 20°C to 25°C (68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Otsuka, NETHERLANDS
Package Size
56s
Price & Supplier
Price in UAE: AED 21284.20
Dosage Information
Adult Dose
Initial dose of 60 mg once daily; may be increased to 90 mg once daily based on tolerability and clinical response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Common side effects include thirst, dry mouth, increased urination, and potential liver enzyme elevations
Contraindications & Precautions
Hypersensitivity to tolvaptan or any component of the formulation; patients with severe liver impairment; concurrent use with strong CYP3A inhibitors
Important Warnings
Risk of liver injury; monitor liver function tests; risk of dehydration and hypotension; not recommended for use in patients with a history of liver disease or those requiring urgent treatment for hyponatremia
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.