About Tolvaptan
Class: | Vasopressin receptor antagonist
Use: | Treatment of hyponatremia (low sodium levels) in patients with heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Adult dose: | Initial dose of 15 mg once daily; may be increased to 30 mg once daily based on serum sodium levels and clinical response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Common side effects include thirst, dry mouth, increased u
Drug Class
Vasopressin receptor antagonist
Uses & Indications
Treatment of hyponatremia (low sodium levels) in patients with heart failure, cirrhosis, and syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Otsuka Pharmaceutical, CANADA
Package Size
10s
Price & Supplier
Price in UAE: AED 4643.00
Dosage Information
Adult Dose
Initial dose of 15 mg once daily; may be increased to 30 mg once daily based on serum sodium levels and clinical response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Common side effects include thirst, dry mouth, increased urination, and nausea
Contraindications & Precautions
Hypersensitivity to tolvaptan or any component of the formulation; anuria; concurrent use with strong CYP3A4 inhibitors
Important Warnings
Risk of hepatotoxicity; monitor liver function tests; may cause rapid increases in serum sodium levels, leading to osmotic demyelination syndrome; not recommended for use in patients with severe liver impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.