About Lapatinib Tosilate (Ditosylate)
Class: | Tyrosine kinase inhibitor
Use: | Treatment of advanced or metastatic breast cancer, particularly in combination with capecitabine in patients with HER2-positive tumors
Adult dose: | 1250 mg orally once daily, taken continuously in combination with capecitabine
Pediatric dose: | Safety and efficacy not established in pediatric populations
Side effects: | Diarrhea, nausea, vomiting, fatigue, rash, hepatotoxicity, and decreased appetite
Contraindications: | Hypersensitivity to la
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of advanced or metastatic breast cancer, particularly in combination with capecitabine in patients with HER2-positive tumors
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Glaxo Operations UK Ltd., UNITED KINGDOM
Package Size
70's (10's Blister x 7)
Price & Supplier
Price in UAE: AED 6038.00
Dosage Information
Adult Dose
1250 mg orally once daily, taken continuously in combination with capecitabine
Pediatric Dose
Safety and efficacy not established in pediatric populations
Side Effects
Diarrhea, nausea, vomiting, fatigue, rash, hepatotoxicity, and decreased appetite
Contraindications & Precautions
Hypersensitivity to lapatinib or any component of the formulation; severe hepatic impairment
Important Warnings
Risk of severe liver toxicity; monitor liver function tests; caution in patients with cardiac conditions due to potential for QT prolongation; avoid use during pregnancy due to potential fetal harm
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.