Nilotinib Hydrochloride (TASIGNA) – Uses, Dosage & Brands in UAE

About Nilotinib Hydrochloride

Class: | Tyrosine kinase inhibitor Use: | Treatment of chronic myeloid leukemia (CML) in adult and pediatric patients with Philadelphia chromosome-positive (Ph+) CML in chronic phase, accelerated phase, or blast crisis Adult dose: | 300 mg orally twice daily, taken at least 12 hours apart Pediatric dose: | 230 mg/m² orally twice daily (maximum 400 mg per dose) Side effects: | Nausea, headache, fatigue, rash, diarrhea, abdominal pain, elevated liver enzymes, and peripheral edema Contrai

Drug Class

Tyrosine kinase inhibitor

Uses & Indications

Treatment of chronic myeloid leukemia (CML) in adult and pediatric patients with Philadelphia chromosome-positive (Ph+) CML in chronic phase, accelerated phase, or blast crisis

Storage Requirements

Store at 20°C to 25°C (68°F to 77°F); protect from light and moisture

Manufacturer & Packaging

Manufacturer: Novartis Pharma AG, SWITZERLAND

Package Size

28's (4's Blister x 7)

Price & Supplier

Price in UAE: AED 4724.00

Dosage Information

Adult Dose

300 mg orally twice daily, taken at least 12 hours apart

Pediatric Dose

230 mg/m² orally twice daily (maximum 400 mg per dose)

Side Effects

Nausea, headache, fatigue, rash, diarrhea, abdominal pain, elevated liver enzymes, and peripheral edema

Contraindications & Precautions

Hypersensitivity to nilotinib or any component of the formulation; prolonged QT interval; hypokalemia; hypomagnesemia; concurrent use with strong CYP3A4 inhibitors

Important Warnings

Risk of QT prolongation and sudden death; monitor ECG and electrolytes; risk of pancreatitis; risk of arterial occlusive events; avoid use in patients with severe hepatic impairment; not recommended for use in pregnancy unless clearly needed

Other Brands & Strengths Available in UAE

Different brands and strengths of Nilotinib Hydrochloride available in UAE pharmacies:

TASIGNA 150 mg Capsules TASIGNA 150 mg Capsules TASIGNA 200 mg Capsules TASIGNA 200 mg Capsules

Related Medicines in Same Category

See also: Other Tyrosine kinase inhibitor medicines available in UAE pharmacies

Afatinib Dimaleate Afatinib Dimaleate Afatinib Dimaleate Afatinib Dimaleate Asciminib Asciminib Avapritinib Avapritinib

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Nilotinib Hydrochloride – Uses, Dosage, and Brands in UAE