About Olipudase alfa
Class: | Enzyme replacement therapy
Use: | Treatment of acid sphingomyelinase deficiency (ASMD), also known as Niemann-Pick disease type A and B
Adult dose: | 1 mg/kg body weight administered every two weeks via intravenous infusion
Pediatric dose: | 1 mg/kg body weight administered every two weeks via intravenous infusion for patients aged 1 year and older
Side effects: | Infusion-related reactions, headache, abdominal pain, diarrhea, nausea, fatigue, and rash
Contraindications: | Hyp
Drug Class
Enzyme replacement therapy
Uses & Indications
Treatment of acid sphingomyelinase deficiency (ASMD), also known as Niemann-Pick disease type A and B
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once reconstituted, use immediately or store for a maximum of 24 hours at 2°C to 8°C
Manufacturer & Packaging
Manufacturer: Genzyme Europe B.V., NETHERLANDS
Package Size
1 Glass Vial
Price & Supplier
Price in UAE: AED 19541.00
Dosage Information
Adult Dose
1 mg/kg body weight administered every two weeks via intravenous infusion
Pediatric Dose
1 mg/kg body weight administered every two weeks via intravenous infusion for patients aged 1 year and older
Side Effects
Infusion-related reactions, headache, abdominal pain, diarrhea, nausea, fatigue, and rash
Contraindications & Precautions
Hypersensitivity to olipudase alfa or any component of the formulation; caution in patients with a history of severe allergic reactions
Important Warnings
Risk of serious allergic reactions; monitor patients during and after infusion; consider premedication with antihistamines and/or corticosteroids for patients with a history of allergic reactions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.