About Dabigatran Etexilate Mesilate
Class: | Anticoagulant (Direct Thrombin Inhibitor)
Use: | Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation; treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE); prevention of DVT and PE in patients undergoing hip or knee replacement surgery.
Adult dose: | 110 mg orally twice daily for non-valvular atrial fibrillation; 150 mg orally twice daily for treatment of DVT/PE; 110 mg orally once daily for DVT/PE prevention aft
Drug Class
Anticoagulant (Direct Thrombin Inhibitor)
Uses & Indications
Prevention of stroke and systemic embolism in patients with non-valvular atrial fibrillation; treatment and prevention of deep vein thrombosis (DVT) and pulmonary embolism (PE); prevention of DVT and PE in patients undergoing hip or knee replacement surgery.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture; keep in original container.
Manufacturer & Packaging
Manufacturer: Boehringer Ingelheim Pharma GmbH & CO. KG, GERMANY
Package Size
60's (10's Blister x 6)
Price & Supplier
Price in UAE: AED 416.50
Dosage Information
Adult Dose
110 mg orally twice daily for non-valvular atrial fibrillation; 150 mg orally twice daily for treatment of DVT/PE; 110 mg orally once daily for DVT/PE prevention after surgery (starting 1-4 hours after surgery).
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children.
Side Effects
Common side effects include gastrointestinal disturbances (nausea, dyspepsia, abdominal pain), bleeding complications (e.g., bruising, hematoma), and increased liver enzymes.
Contraindications & Precautions
Active bleeding, severe renal impairment (CrCl < 15 mL/min), mechanical prosthetic heart valves, hypersensitivity to dabigatran or any component of the formulation.
Important Warnings
Increased risk of bleeding; monitor renal function; discontinue prior to surgical procedures; not recommended for patients with active bleeding or significant bleeding risk; use caution in elderly patients and those with renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.