About Mercaptopurine
Class: | Antimetabolite, Purine analog
Use: | Treatment of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML); also used in the management of Crohn's disease and ulcerative colitis
Adult dose: | Initial dose is typically 1.5 to 2.5 mg/kg/day, adjusted based on clinical response and tolerance
Pediatric dose: | Initial dose is generally 1.5 to 2.5 mg/kg/day, with adjustments made based on clinical response and tolerance
Side effects: | Nausea, vomiting, diarrhea, liver tox
Drug Class
Antimetabolite, Purine analog
Uses & Indications
Treatment of acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML); also used in the management of Crohn's disease and ulcerative colitis
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from light and moisture
Manufacturer & Packaging
Manufacturer: Excella GmbH, GERMANY
Package Size
25's Glass Bottle
Price & Supplier
Price in UAE: AED 369.50
Dosage Information
Adult Dose
Initial dose is typically 1.5 to 2.5 mg/kg/day, adjusted based on clinical response and tolerance
Pediatric Dose
Initial dose is generally 1.5 to 2.5 mg/kg/day, with adjustments made based on clinical response and tolerance
Side Effects
Nausea, vomiting, diarrhea, liver toxicity, bone marrow suppression, increased risk of infections, rash
Contraindications & Precautions
Hypersensitivity to mercaptopurine or any component of the formulation; severe liver impairment; concurrent use with allopurinol without dose adjustment
Important Warnings
Risk of myelosuppression; monitor blood counts regularly; potential for hepatotoxicity; avoid live vaccines during treatment; may cause fetal harm if used during pregnancy
Related Medicines in Same Category
See also: Other Antimetabolite, Purine analog medicines available in UAE pharmacies
Thioguanine
Thioguanine
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.