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Sebelipase Alfa – Uses, Dosage, and Brands in UAE

Brand Name: Kanuma
Strength: 2 mg/1 ml | Form: Concentrate For Solution For Infusion
Price in UAE: AED 35603.50
Available in UAE pharmacies

About Sebelipase Alfa

Class: | Enzyme replacement therapy (ERT) Use: | Treatment of lysosomal acid lipase deficiency (LAL-D), including Wolman disease and cholesteryl ester storage disease (CESD) Adult dose: | 1 mg/kg body weight administered once every two weeks via intravenous infusion Pediatric dose: | 1 mg/kg body weight administered once every two weeks via intravenous infusion; dosing may vary based on clinical response and tolerability Side effects: | Common side effects include infusion-related reacti

Drug Class

Enzyme replacement therapy (ERT)

Uses & Indications

Treatment of lysosomal acid lipase deficiency (LAL-D), including Wolman disease and cholesteryl ester storage disease (CESD)

Storage Requirements

Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once diluted, the solution should be used immediately or stored at room temperature for up to 24 hours

Manufacturer & Packaging

Manufacturer: Alexion Europe SAS [Levallois-Perret;France], France

Package Size

1 Glass Vial (10 ml)

Price & Supplier

Price in UAE: AED 35603.50

Dosage Information

Adult Dose

1 mg/kg body weight administered once every two weeks via intravenous infusion

Pediatric Dose

1 mg/kg body weight administered once every two weeks via intravenous infusion; dosing may vary based on clinical response and tolerability

Side Effects

Common side effects include infusion-related reactions (fever, chills, rash), gastrointestinal symptoms (diarrhea, vomiting), headache, and elevated liver enzymes

Contraindications & Precautions

Hypersensitivity to the active substance or any of the excipients; caution in patients with a history of severe allergic reactions

Important Warnings

Risk of serious hypersensitivity reactions; monitor patients for signs of anaphylaxis during and after infusion; consider premedication with antihistamines or corticosteroids for patients with a history of allergic reactions to infusions

Related Medicines in Same Category

See also: Other Enzyme replacement therapy (ERT) medicines available in UAE pharmacies

Agalsidase alfa Agalsidase alfa Agalsidase beta Agalsidase beta Alfa Glucosidaze-Myozyme Alfa Glucosidaze-Myozyme Galsulfase Galsulfase

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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