About Selpercatinib
Class: | Tyrosine kinase inhibitor
Use: | Treatment of adults with non-small cell lung cancer (NSCLC) that is RET fusion-positive, and for adults and pediatric patients 12 years and older with advanced or metastatic medullary thyroid cancer (MTC)
Adult dose: | 120 mg orally once daily; may be taken with or without food
Pediatric dose: | Safety and efficacy not established in patients under 12 years; dosing for patients 12 years and older is based on body weight: 120 mg orally once daily fo
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of adults with non-small cell lung cancer (NSCLC) that is RET fusion-positive, and for adults and pediatric patients 12 years and older with advanced or metastatic medullary thyroid cancer (MTC)
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Eli Lilly & Co Inc., U.S.A
Package Size
60's HDPE Bottle
Price & Supplier
Price in UAE: AED 15867.50
Dosage Information
Adult Dose
120 mg orally once daily; may be taken with or without food
Pediatric Dose
Safety and efficacy not established in patients under 12 years; dosing for patients 12 years and older is based on body weight: 120 mg orally once daily for those weighing 50 kg or more, and 80 mg orally once daily for those weighing less than 50 kg
Side Effects
Common side effects include diarrhea, fatigue, nausea, hypertension, and increased liver enzymes
Contraindications & Precautions
Hypersensitivity to selpercatinib or any component of the formulation; caution in patients with severe hepatic impairment
Important Warnings
Risk of hepatotoxicity, QT prolongation, and severe hypertension; monitor liver function tests and blood pressure regularly; may cause embryo-fetal toxicity; advise females of reproductive potential to use effective contraception during treatment and for at least 1 week after the last dose
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.