About Methylprednisolone Sodium Succinate
Class: | Corticosteroid
Use: | Methylprednisolone Sodium Succinate is used for the treatment of various inflammatory and autoimmune conditions, including but not limited to severe allergies, asthma, rheumatoid arthritis, lupus, multiple sclerosis exacerbations, and certain skin conditions. It is also used in the management of certain types of shock and to prevent organ transplant rejection.
Adult dose: | The typical adult dose varies based on the condition being treated, but it generally ran
Drug Class
Corticosteroid
Uses & Indications
Methylprednisolone Sodium Succinate is used for the treatment of various inflammatory and autoimmune conditions, including but not limited to severe allergies, asthma, rheumatoid arthritis, lupus, multiple sclerosis exacerbations, and certain skin conditions. It is also used in the management of certain types of shock and to prevent organ transplant rejection.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F) in a dry place, protected from light. Once reconstituted, the solution should be used immediately or stored in the refrigerator and used within 24 hours.
Manufacturer & Packaging
Manufacturer: Pfizer Manufacturing N.V., BELGIUM
Package Size
1 Act-o-Vial (Powder + 1ml Solvent) Preservative-Free
Price & Supplier
Price in UAE: AED 12.00
Dosage Information
Adult Dose
The typical adult dose varies based on the condition being treated, but it generally ranges from 10 mg to 40 mg administered intravenously or intramuscularly. Dosing may be repeated every 4 to 6 hours as needed, and higher doses may be used in acute situations.
Pediatric Dose
The pediatric dose is typically 0.5 to 1 mg/kg administered intravenously or intramuscularly, not to exceed 60 mg per day. Dosing may vary based on the specific condition and clinical judgment.
Side Effects
Common side effects include insomnia, mood changes, increased appetite, weight gain, fluid retention, elevated blood glucose levels, gastrointestinal disturbances, and increased risk of infections.
Contraindications & Precautions
Contraindicated in patients with systemic fungal infections, known hypersensitivity to methylprednisolone or any component of the formulation, and in patients receiving live vaccines. Caution is advised in patients with peptic ulcer disease, diabetes, hypertension, and osteoporosis.
Important Warnings
Long-term use may lead to adrenal suppression, Cushing's syndrome, and other serious side effects. Abrupt discontinuation after prolonged therapy can result in withdrawal symptoms. Patients should be monitored for signs of infection, and vaccinations should be updated prior to initiation of therapy.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.