About Tolvaptan
Class: | Vasopressin receptor antagonist
Use: | Treatment of autosomal dominant polycystic kidney disease (ADPKD) to slow the progression of kidney function decline
Adult dose: | Initial dose of 15 mg orally once daily; may be increased to 30 mg once daily based on tolerability and response
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children
Side effects: | Common side effects include thirst, dry mouth, increased urination, and
Drug Class
Vasopressin receptor antagonist
Uses & Indications
Treatment of autosomal dominant polycystic kidney disease (ADPKD) to slow the progression of kidney function decline
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Par Pharmaceutical Inc., U.S.A
Package Size
10's
Price & Supplier
Price in UAE: AED 2430.70
Dosage Information
Adult Dose
Initial dose of 15 mg orally once daily; may be increased to 30 mg once daily based on tolerability and response
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children
Side Effects
Common side effects include thirst, dry mouth, increased urination, and hypotension
Contraindications & Precautions
Hypersensitivity to tolvaptan or any component of the formulation; anuria; severe liver impairment (Child-Pugh Class C)
Important Warnings
Risk of liver injury; monitor liver function tests; may cause dehydration and hypotension; not for use in patients with significant liver disease or those requiring rapid correction of hyponatremia
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.