About Tucatinib hemiethanolate 52.40 mg equivalent to Tucatinib 50 mg
Class: | Tyrosine kinase inhibitor
Use: | Treatment of adult patients with unresectable locally advanced or metastatic HER2-positive breast cancer, in combination with capecitabine, particularly in patients who have received at least one prior anti-HER2-based regimen.
Adult dose: | 300 mg orally twice daily, taken with food.
Pediatric dose: | Safety and efficacy in pediatric patients have not been established; not recommended for use in children.
Side effects: | Diarrhea, nausea, fatigue
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of adult patients with unresectable locally advanced or metastatic HER2-positive breast cancer, in combination with capecitabine, particularly in patients who have received at least one prior anti-HER2-based regimen.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Pfizer Europe MA EEIG [Bruxells;BELGIUM], Belgium
Package Size
88's (8's Blister x 11)
Price & Supplier
Price in UAE: AED 10522.50
Dosage Information
Adult Dose
300 mg orally twice daily, taken with food.
Pediatric Dose
Safety and efficacy in pediatric patients have not been established; not recommended for use in children.
Side Effects
Diarrhea, nausea, fatigue, liver enzyme elevations, rash, and decreased appetite.
Contraindications & Precautions
Hypersensitivity to tucatinib or any component of the formulation; severe hepatic impairment (Child-Pugh Class C).
Important Warnings
Risk of severe diarrhea, hepatotoxicity, and embryo-fetal toxicity; monitor liver function tests and manage diarrhea proactively. Pregnant women should be advised of the potential risk to the fetus.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.