About Spironolactone
Class: | Potassium-sparing diuretic
Use: | Treatment of hypertension, edema associated with heart failure, cirrhosis of the liver, and nephrotic syndrome; also used for primary hyperaldosteronism
Adult dose: | Initial: 100 mg orally once daily; may be adjusted based on clinical response, typically up to 400 mg/day in divided doses
Pediatric dose: | Not established; use in children should be based on clinical judgment and careful monitoring
Side effects: | Hyperkalemia, hyponatremia, dizz
Drug Class
Potassium-sparing diuretic
Uses & Indications
Treatment of hypertension, edema associated with heart failure, cirrhosis of the liver, and nephrotic syndrome; also used for primary hyperaldosteronism
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from light and moisture
Manufacturer & Packaging
Manufacturer: Searle Pharmaceuticals, UNITED KINGDOM
Package Size
10's
Price & Supplier
Price in UAE: AED 37.00
Dosage Information
Adult Dose
Initial: 100 mg orally once daily; may be adjusted based on clinical response, typically up to 400 mg/day in divided doses
Pediatric Dose
Not established; use in children should be based on clinical judgment and careful monitoring
Side Effects
Hyperkalemia, hyponatremia, dizziness, gastrointestinal disturbances, menstrual irregularities, breast tenderness, and gynecomastia
Contraindications & Precautions
Anuria, acute renal insufficiency, significant renal impairment (creatinine clearance < 30 mL/min), hyperkalemia, and Addison's disease
Important Warnings
Monitor potassium levels regularly; use caution in patients with renal impairment, diabetes, or those taking other medications that may increase potassium levels; may cause hypotension, especially when used with other antihypertensives.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.