About Spironolactone
Class: | Potassium-sparing diuretic
Use: | Treatment of hypertension, edema associated with heart failure, cirrhosis of the liver, and nephrotic syndrome; also used for conditions like primary hyperaldosteronism
Adult dose: | Initial dose of 25 mg to 100 mg per day, adjusted based on clinical response; typical maintenance dose is 25 mg to 50 mg per day
Pediatric dose: | Not established; use in children should be based on clinical judgment and careful monitoring
Side effects: | Hyperkalem
Drug Class
Potassium-sparing diuretic
Uses & Indications
Treatment of hypertension, edema associated with heart failure, cirrhosis of the liver, and nephrotic syndrome; also used for conditions like primary hyperaldosteronism
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from light and moisture
Manufacturer & Packaging
Manufacturer: REMEDICA LTD, CYPRUS
Package Size
50'S
Price & Supplier
Price in UAE: AED 6.16
Dosage Information
Adult Dose
Initial dose of 25 mg to 100 mg per day, adjusted based on clinical response; typical maintenance dose is 25 mg to 50 mg per day
Pediatric Dose
Not established; use in children should be based on clinical judgment and careful monitoring
Side Effects
Hyperkalemia, hypotension, dizziness, gastrointestinal disturbances (nausea, vomiting, diarrhea), menstrual irregularities, breast tenderness or enlargement
Contraindications & Precautions
Anuria, acute renal insufficiency, significant renal impairment (creatinine clearance < 30 mL/min), hyperkalemia, Addison's disease, and hypersensitivity to spironolactone or any component of the formulation
Important Warnings
Monitor potassium levels regularly; use caution in patients with renal impairment, diabetes, or those on other medications that may increase potassium levels; avoid concomitant use with ACE inhibitors or ARBs without close monitoring
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.