About Spironolactone
Class: | Potassium-sparing diuretic; Aldosterone antagonist
Use: | Treatment of hypertension, heart failure, edema associated with congestive heart failure, cirrhosis of the liver, and nephrotic syndrome; primary hyperaldosteronism diagnosis and treatment; hirsutism and acne in females
Adult dose: | Hypertension: 25-100 mg per day in single or divided doses; Heart failure: 12.5-25 mg per day; Edema: 25-200 mg per day in single or divided doses
Pediatric dose: | Edema: 1-3 mg/kg/day in sing
Drug Class
Potassium-sparing diuretic; Aldosterone antagonist
Uses & Indications
Treatment of hypertension, heart failure, edema associated with congestive heart failure, cirrhosis of the liver, and nephrotic syndrome; primary hyperaldosteronism diagnosis and treatment; hirsutism and acne in females
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture
Manufacturer & Packaging
Manufacturer: Genethics Europe Limited, Cyprus
Package Size
28's
Price & Supplier
Price in UAE: AED 19.75
Dosage Information
Adult Dose
Hypertension: 25-100 mg per day in single or divided doses; Heart failure: 12.5-25 mg per day; Edema: 25-200 mg per day in single or divided doses
Pediatric Dose
Edema: 1-3 mg/kg/day in single or divided doses (maximum 100 mg/day)
Side Effects
Hyperkalemia, gynecomastia, menstrual irregularities, dizziness, headache, gastrointestinal disturbances, rash
Contraindications & Precautions
Anuria, acute renal insufficiency, significant renal impairment, hyperkalemia, Addison's disease, hypersensitivity to spironolactone
Important Warnings
Risk of hyperkalemia, especially in patients with renal impairment or those taking other potassium-sparing medications; monitor electrolytes regularly; caution in patients with liver disease; may cause tumorigenic effects in chronic toxicity studies in rats; use only for approved indications
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.