About Laronidase
Class: | Enzyme replacement therapy
Use: | Treatment of mucopolysaccharidosis type I (MPS I), specifically for patients with Hurler syndrome or Hurler-Scheie syndrome
Adult dose: | 0.58 mg/kg (approximately 1.2 units/kg) administered intravenously every week
Pediatric dose: | 0.58 mg/kg (approximately 1.2 units/kg) administered intravenously every week; dosing is the same for pediatric patients
Side effects: | Fever, chills, rash, headache, nausea, vomiting, abdominal pain, and infusion-
Drug Class
Enzyme replacement therapy
Uses & Indications
Treatment of mucopolysaccharidosis type I (MPS I), specifically for patients with Hurler syndrome or Hurler-Scheie syndrome
Storage Requirements
Store at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light; once diluted, use immediately or store at 2°C to 8°C for up to 24 hours
Manufacturer & Packaging
Manufacturer: Genzyme Europe B.V., NETHERLANDS
Package Size
5ml Vial
Price & Supplier
Price in UAE: AED 2665.70
Dosage Information
Adult Dose
0.58 mg/kg (approximately 1.2 units/kg) administered intravenously every week
Pediatric Dose
0.58 mg/kg (approximately 1.2 units/kg) administered intravenously every week; dosing is the same for pediatric patients
Side Effects
Fever, chills, rash, headache, nausea, vomiting, abdominal pain, and infusion-related reactions
Contraindications & Precautions
Hypersensitivity to Laronidase or any component of the formulation; caution in patients with a history of severe allergic reactions
Important Warnings
Risk of anaphylaxis; monitor patients for hypersensitivity reactions during and after infusion; may cause infusion-related reactions; consider premedication with antihistamines and/or antipyretics for patients with a history of reactions
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.