About Bosutinib
Class: | Tyrosine kinase inhibitor
Use: | Treatment of chronic myelogenous leukemia (CML) in adults with resistance or intolerance to prior therapy
Adult dose: | Initial dose is 500 mg once daily; may be increased to 600 mg once daily based on tolerance and response
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Diarrhea, nausea, vomiting, fatigue, headache, rash, liver enzyme elevations, and myelosuppression
Contraindications: | Hypersensit
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of chronic myelogenous leukemia (CML) in adults with resistance or intolerance to prior therapy
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: PFIZER EUROPE MA EEIG, BELGIUM
Package Size
28s
Price & Supplier
Price in UAE: AED 5172.50
Dosage Information
Adult Dose
Initial dose is 500 mg once daily; may be increased to 600 mg once daily based on tolerance and response
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Diarrhea, nausea, vomiting, fatigue, headache, rash, liver enzyme elevations, and myelosuppression
Contraindications & Precautions
Hypersensitivity to bosutinib or any component of the formulation; severe hepatic impairment
Important Warnings
Risk of severe diarrhea, liver toxicity, and myelosuppression; monitor liver function and blood counts regularly; use caution in patients with a history of cardiac arrhythmias or those taking medications that prolong the QT interval
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.