About Capecitabine
Class: | Antimetabolite, Antineoplastic agent
Use: | Capecitabine is used primarily for the treatment of metastatic colorectal cancer and metastatic breast cancer. It may also be used in combination with other medications for the treatment of gastric cancer and other types of cancer as determined by a healthcare provider.
Adult dose: | The standard adult dose for metastatic colorectal cancer is 1250 mg/m² orally twice daily for 14 days followed by a 7-day rest period, in a 21-day cycle. For
Drug Class
Antimetabolite, Antineoplastic agent
Uses & Indications
Capecitabine is used primarily for the treatment of metastatic colorectal cancer and metastatic breast cancer. It may also be used in combination with other medications for the treatment of gastric cancer and other types of cancer as determined by a healthcare provider.
Storage Requirements
Store at room temperature, between 20°C to 25°C (68°F to 77°F), in a dry place away from light and moisture. Keep out of reach of children.
Manufacturer & Packaging
Manufacturer: Al Hikma Pharmaceuticals, JORDAN
Package Size
120s
Price & Supplier
Price in UAE: AED 869.50
Dosage Information
Adult Dose
The standard adult dose for metastatic colorectal cancer is 1250 mg/m² orally twice daily for 14 days followed by a 7-day rest period, in a 21-day cycle. For metastatic breast cancer, the dose is often 1250 mg/m² orally twice daily for 14 days followed by a 7-day rest period, in combination with other chemotherapy agents. Dosage may vary based on specific treatment protocols and patient factors.
Pediatric Dose
Capecitabine is not typically used in pediatric patients, and dosing information is not established for this population. Use in children should be determined by a specialist.
Side Effects
Common side effects include diarrhea, nausea, vomiting, stomatitis, hand-foot syndrome (palmar-plantar erythrodysesthesia), fatigue, and abdominal pain.
Contraindications & Precautions
Contraindicated in patients with severe renal impairment (creatinine clearance below 30 mL/min), known hypersensitivity to capecitabine or any of its components, and in patients with known dihydropyrimidine dehydrogenase (DPD) deficiency.
Important Warnings
Capecitabine can cause severe diarrhea, dehydration, and hand-foot syndrome. It may also lead to cardiotoxicity, particularly in patients with a history of coronary artery disease. Monitor blood counts regularly due to the risk of myelosuppression. Use with caution in patients with hepatic impairment. Adjust dose in patients with moderate renal impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.