About Alteplase
Class: | Thrombolytic agent
Use: | Indicated for the restoration of function in occluded central venous access devices (CVADs) due to thrombus formation.
Adult dose: | 2 mg administered as a single dose directly into the occluded CVAD, infused over 30 minutes.
Pediatric dose: | Not established; safety and efficacy in pediatric patients have not been determined.
Side effects: | Common side effects include bleeding, headache, nausea, and hypotension.
Contraindications: | Active internal
Drug Class
Thrombolytic agent
Uses & Indications
Indicated for the restoration of function in occluded central venous access devices (CVADs) due to thrombus formation.
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light. Reconstituted solution should be used immediately or stored at 2°C to 8°C (36°F to 46°F) for up to 8 hours.
Manufacturer & Packaging
Manufacturer: Hoffmann-La Roche Ltd, Canada
Package Size
10
Price & Supplier
Price in UAE: AED 4312.00
Dosage Information
Adult Dose
2 mg administered as a single dose directly into the occluded CVAD, infused over 30 minutes.
Pediatric Dose
Not established; safety and efficacy in pediatric patients have not been determined.
Side Effects
Common side effects include bleeding, headache, nausea, and hypotension.
Contraindications & Precautions
Active internal bleeding, recent intracranial or intraspinal surgery, severe uncontrolled hypertension, known hypersensitivity to alteplase or any component of the formulation.
Important Warnings
Risk of serious bleeding; monitor for signs of bleeding during and after administration. Use caution in patients with a history of bleeding disorders, recent surgery, or trauma.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.