Colistimethate Sodium (COLISTIN HIKMA) – Uses, Dosage & Brands in UAE

About Colistimethate Sodium

Class: | Polymyxin antibiotic Use: | Colistimethate Sodium is used for the treatment of certain infections caused by multidrug-resistant Gram-negative bacteria, including Pseudomonas aeruginosa and Acinetobacter baumannii. It is often reserved for severe infections where other antibiotics are ineffective. Adult dose: | For intravenous administration, the typical dose is 2.5 to 5 mg/kg/day of colistin base activity, divided into 2 to 4 doses. For nebulization, the dose is typically 75 to 150 mg

Drug Class

Polymyxin antibiotic

Uses & Indications

Colistimethate Sodium is used for the treatment of certain infections caused by multidrug-resistant Gram-negative bacteria, including Pseudomonas aeruginosa and Acinetobacter baumannii. It is often reserved for severe infections where other antibiotics are ineffective.

Storage Requirements

Store the powder at room temperature, away from moisture and heat. Reconstituted solutions should be used immediately or stored in a refrigerator and used within 24 hours.

Manufacturer & Packaging

Manufacturer: Al Hikma Pharmaceuticals, JORDAN

Package Size

10ml Vial

Price & Supplier

Price in UAE: AED 16.50

Dosage Information

Adult Dose

For intravenous administration, the typical dose is 2.5 to 5 mg/kg/day of colistin base activity, divided into 2 to 4 doses. For nebulization, the dose is typically 75 to 150 mg of colistin base activity, 1 to 3 times daily, depending on the severity of the infection and clinical response.

Pediatric Dose

For intravenous administration, the dose is generally 2.5 to 5 mg/kg/day of colistin base activity, divided into 2 to 4 doses. For nebulization, dosing is typically based on clinical judgment and severity of infection, often similar to adult dosing but adjusted for body weight.

Side Effects

Common side effects include nephrotoxicity (kidney damage), neurotoxicity (such as dizziness, tingling, or numbness), respiratory issues when inhaled, and gastrointestinal disturbances like nausea and vomiting.

Important Warnings

Use with caution in patients with renal impairment, as dosage adjustments may be necessary. Monitor renal function regularly during treatment. Be aware of potential neurotoxic effects, especially in patients with neuromuscular disorders. Avoid concurrent use with other nephrotoxic or neurotoxic drugs.

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Colistimethate Sodium – Uses, Dosage, and Brands in UAE