About Entacapone
Class: | COMT inhibitor
Use: | Adjunctive treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing "wearing-off" phenomena
Adult dose: | 200 mg taken with each dose of levodopa/carbidopa, up to 8 times daily (maximum 1600 mg/day)
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Diarrhea, dyskinesia, nausea, abdominal pain, urine discoloration (brownish), and insomnia
Contraindications: | Hypersensitivity to entacapone
Drug Class
COMT inhibitor
Uses & Indications
Adjunctive treatment to levodopa/carbidopa in patients with Parkinson's disease experiencing "wearing-off" phenomena
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Novartis Pharma AG, SWITZERLAND
Package Size
30's Glass Bottle
Price & Supplier
Price in UAE: AED 173.50
Dosage Information
Adult Dose
200 mg taken with each dose of levodopa/carbidopa, up to 8 times daily (maximum 1600 mg/day)
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Diarrhea, dyskinesia, nausea, abdominal pain, urine discoloration (brownish), and insomnia
Contraindications & Precautions
Hypersensitivity to entacapone or any component of the formulation; concomitant use with non-selective monoamine oxidase inhibitors (MAOIs)
Important Warnings
May cause severe liver injury; monitor liver function tests; caution in patients with liver impairment; may exacerbate dyskinesia in patients with Parkinson's disease.
Related Medicines in Same Category
See also: Other COMT inhibitor medicines available in UAE pharmacies
Opicapone
Opicapone
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.