About Actinomycin D (Dactinomycin)
Class: | Antineoplastic agent, Antibiotic
Use: | Treatment of various cancers including Wilms' tumor, rhabdomyosarcoma, and testicular cancer; also used in some cases of gestational trophoblastic neoplasia
Adult dose: | 12 to 15 mcg/kg IV once every 1 to 2 weeks, depending on the specific cancer being treated
Pediatric dose: | 15 mcg/kg IV once every 1 to 2 weeks for Wilms' tumor and other indications, adjusted based on clinical response and tolerance
Side effects: | Nausea, vomiting, my
Drug Class
Antineoplastic agent, Antibiotic
Uses & Indications
Treatment of various cancers including Wilms' tumor, rhabdomyosarcoma, and testicular cancer; also used in some cases of gestational trophoblastic neoplasia
Storage Requirements
Store at 20-25°C (68-77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: KOREA UNITED PHARMA INC, KOREA SOUTH
Package Size
Dry Powder Vial
Price & Supplier
Price in UAE: AED 117.30
Dosage Information
Adult Dose
12 to 15 mcg/kg IV once every 1 to 2 weeks, depending on the specific cancer being treated
Pediatric Dose
15 mcg/kg IV once every 1 to 2 weeks for Wilms' tumor and other indications, adjusted based on clinical response and tolerance
Side Effects
Nausea, vomiting, myelosuppression, mucositis, alopecia, and potential for secondary malignancies
Contraindications & Precautions
Hypersensitivity to actinomycin D or any component of the formulation; pregnancy (category D); severe bone marrow suppression
Important Warnings
Risk of severe myelosuppression; monitor blood counts regularly; potential for hepatotoxicity; may cause fetal harm if administered during pregnancy; use caution in patients with liver impairment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.