About Actinomycin D (Dactinomycin)
Class: | Antineoplastic agent, Antibiotic
Use: | Treatment of various cancers including Wilms' tumor, rhabdomyosarcoma, and gestational trophoblastic neoplasia
Adult dose: | 12 to 15 mcg/kg IV every 1 to 2 weeks, depending on the specific cancer and treatment protocol
Pediatric dose: | 15 mcg/kg IV every 1 to 2 weeks for Wilms' tumor; dosing may vary based on specific indications
Side effects: | Nausea, vomiting, myelosuppression, mucositis, alopecia, and potential for severe tissue necr
Drug Class
Antineoplastic agent, Antibiotic
Uses & Indications
Treatment of various cancers including Wilms' tumor, rhabdomyosarcoma, and gestational trophoblastic neoplasia
Storage Requirements
Store at 20-25°C (68-77°F); protect from light and moisture; do not freeze
Manufacturer & Packaging
Manufacturer: MSD, U.S.A
Package Size
1 Vial
Price & Supplier
Price in UAE: AED 120.74
Dosage Information
Adult Dose
12 to 15 mcg/kg IV every 1 to 2 weeks, depending on the specific cancer and treatment protocol
Pediatric Dose
15 mcg/kg IV every 1 to 2 weeks for Wilms' tumor; dosing may vary based on specific indications
Side Effects
Nausea, vomiting, myelosuppression, mucositis, alopecia, and potential for severe tissue necrosis at injection site
Contraindications & Precautions
Hypersensitivity to actinomycin D, pregnancy (category X), breastfeeding, and severe bone marrow suppression
Important Warnings
Risk of severe myelosuppression, potential for secondary malignancies, and caution in patients with liver or kidney impairment; monitor for signs of infection and bleeding
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.