About Imatinib Mesylate
Class: | Tyrosine kinase inhibitor
Use: | Treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other malignancies associated with specific genetic mutations (e.g., PDGFRA).
Adult dose: | 400 mg once daily for CML; 400 mg to 600 mg once daily for GISTs, depending on the specific indication and patient response.
Pediatric dose: | For CML, 340 mg/m² once daily (maximum 600 mg); for GISTs, dosing is based on body surface area and should be determined by a h
Drug Class
Tyrosine kinase inhibitor
Uses & Indications
Treatment of chronic myeloid leukemia (CML), gastrointestinal stromal tumors (GISTs), and other malignancies associated with specific genetic mutations (e.g., PDGFRA).
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light.
Manufacturer & Packaging
Manufacturer: Apotex Inc., CANADA
Package Size
30's (10's Blister x 3 )
Price & Supplier
Price in UAE: AED 613.00
Dosage Information
Adult Dose
400 mg once daily for CML; 400 mg to 600 mg once daily for GISTs, depending on the specific indication and patient response.
Pediatric Dose
For CML, 340 mg/m² once daily (maximum 600 mg); for GISTs, dosing is based on body surface area and should be determined by a healthcare provider.
Side Effects
Nausea, vomiting, diarrhea, fatigue, edema, rash, muscle cramps, and liver enzyme elevations.
Contraindications & Precautions
Hypersensitivity to imatinib or any component of the formulation; caution in patients with severe liver impairment.
Important Warnings
Risk of severe myelosuppression, hepatotoxicity, and fluid retention; monitor blood counts and liver function regularly; may cause fetal harm; use caution in patients with cardiac conditions.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.