About Metformin Hydrochloride,Sitagliptin Phosphate
Class: | Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Use: | Management of type 2 diabetes mellitus in adults to improve glycemic control, typically in conjunction with diet and exercise.
Adult dose: | One tablet containing 1000 mg of Metformin and 50 mg of Sitagliptin taken orally once daily, with or without food; dosage may be adjusted based on individual response and tolerability.
Pediatric dose: | Safety and efficacy have not been established in pediatric patient
Drug Class
Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Uses & Indications
Management of type 2 diabetes mellitus in adults to improve glycemic control, typically in conjunction with diet and exercise.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F) in a tightly closed container, protected from moisture and light.
Manufacturer & Packaging
Manufacturer: Merck Sharp & Dohme B.V., NETHERLANDS
Package Size
56's (7's Blister x 8)
Price & Supplier
Price in UAE: AED 201.50
Dosage Information
Adult Dose
One tablet containing 1000 mg of Metformin and 50 mg of Sitagliptin taken orally once daily, with or without food; dosage may be adjusted based on individual response and tolerability.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients under 18 years of age; not recommended for use in this population.
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea, abdominal pain), headache, and upper respiratory tract infections.
Contraindications & Precautions
Contraindicated in patients with a history of hypersensitivity to Metformin or Sitagliptin, severe renal impairment (eGFR < 30 mL/min), acute or chronic metabolic acidosis, including diabetic ketoacidosis.
Important Warnings
Risk of lactic acidosis, particularly in patients with renal impairment, hepatic impairment, or conditions that may predispose to hypoxia; monitor renal function regularly; discontinue if significant renal impairment occurs.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.