About Metformin Hydrochloride,Sitagliptin Phosphate
Class: | Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Use: | Management of type 2 diabetes mellitus in adults to improve glycemic control, often in conjunction with diet and exercise.
Adult dose: | Typically, 1000 mg of Metformin and 50 mg of Sitagliptin taken orally once daily, with adjustments based on individual patient response and tolerability.
Pediatric dose: | Safety and efficacy not established in pediatric patients; not recommended for use in children.
Sid
Drug Class
Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Uses & Indications
Management of type 2 diabetes mellitus in adults to improve glycemic control, often in conjunction with diet and exercise.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F) in a tightly closed container, protected from moisture and light.
Manufacturer & Packaging
Manufacturer: Julphar (Gulf Pharmaceutical Industries), U.A.E
Package Size
56's (7's Blister x 8)
Price & Supplier
Price in UAE: AED 201.50
Dosage Information
Adult Dose
Typically, 1000 mg of Metformin and 50 mg of Sitagliptin taken orally once daily, with adjustments based on individual patient response and tolerability.
Pediatric Dose
Safety and efficacy not established in pediatric patients; not recommended for use in children.
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, and upper respiratory tract infections.
Contraindications & Precautions
Contraindicated in patients with a history of hypersensitivity to Metformin or Sitagliptin, severe renal impairment (eGFR < 30 mL/min), acute or chronic metabolic acidosis, including diabetic ketoacidosis.
Important Warnings
Risk of lactic acidosis, particularly in patients with renal impairment, liver disease, or conditions that may lead to hypoxia. Monitor renal function regularly; discontinue if eGFR falls below 30 mL/min.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.