About Metformin Hydrochloride,Sitagliptin Phosphate
Class: | Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Use: | Management of type 2 diabetes mellitus to improve glycemic control in adults when used in conjunction with diet and exercise
Adult dose: | 1000 mg Metformin Hydrochloride and 100 mg Sitagliptin Phosphate once daily, taken with food to reduce gastrointestinal side effects
Pediatric dose: | Safety and efficacy not established in pediatric patients under 18 years of age
Side effects: | Common side effects in
Drug Class
Antidiabetic combination medication (Biguanide and DPP-4 inhibitor)
Uses & Indications
Management of type 2 diabetes mellitus to improve glycemic control in adults when used in conjunction with diet and exercise
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F) in a tightly closed container, protected from moisture and light
Manufacturer & Packaging
Manufacturer: Merck Sharp & Dohme Corporation, U.S.A
Package Size
28's HDPE Bottle
Price & Supplier
Price in UAE: AED 262.00
Dosage Information
Adult Dose
1000 mg Metformin Hydrochloride and 100 mg Sitagliptin Phosphate once daily, taken with food to reduce gastrointestinal side effects
Pediatric Dose
Safety and efficacy not established in pediatric patients under 18 years of age
Side Effects
Common side effects include gastrointestinal disturbances (nausea, vomiting, diarrhea), headache, and upper respiratory tract infections
Contraindications & Precautions
Contraindicated in patients with a history of hypersensitivity to Metformin or Sitagliptin, severe renal impairment (eGFR < 30 mL/min), acute or chronic metabolic acidosis, including diabetic ketoacidosis
Important Warnings
Risk of lactic acidosis, particularly in patients with renal impairment, liver disease, or conditions that may lead to hypoxia; monitor renal function regularly; discontinue if signs of lactic acidosis occur.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.