About Milrinone
Class: | Phosphodiesterase inhibitor
Use: | Treatment of acute heart failure and severe chronic heart failure; used to improve cardiac output and reduce pulmonary vascular resistance
Adult dose: | Initial bolus of 50 mcg/kg IV over 10 minutes, followed by a continuous infusion of 0.375 to 0.75 mcg/kg/min, titrated based on clinical response
Pediatric dose: | Not established; use in pediatric patients should be based on clinical judgment and specific patient needs
Side effects: | Hypotens
Drug Class
Phosphodiesterase inhibitor
Uses & Indications
Treatment of acute heart failure and severe chronic heart failure; used to improve cardiac output and reduce pulmonary vascular resistance
Storage Requirements
Store at 20°C to 25°C (68°F to 77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Stragen UK Limited, UNITED KINGDOM
Package Size
10ml Ampoule x 10
Price & Supplier
Price in UAE: AED 964.50
Dosage Information
Adult Dose
Initial bolus of 50 mcg/kg IV over 10 minutes, followed by a continuous infusion of 0.375 to 0.75 mcg/kg/min, titrated based on clinical response
Pediatric Dose
Not established; use in pediatric patients should be based on clinical judgment and specific patient needs
Side Effects
Hypotension, arrhythmias, headache, nausea, vomiting, thrombocytopenia, and elevated liver enzymes
Contraindications & Precautions
Hypersensitivity to milrinone or any component of the formulation; severe aortic or pulmonary valvular disease; hypertrophic cardiomyopathy
Important Warnings
Use with caution in patients with renal impairment; monitor for hypotension and arrhythmias; may increase mortality in patients with chronic heart failure when used long-term; not recommended for use in patients with significant hypotension or those requiring high doses of diuretics.
Related Medicines in Same Category
See also: Other Phosphodiesterase inhibitor medicines available in UAE pharmacies
Amrinone
Enoximone
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.