About SELINEXOR
Class: | Antineoplastic agent, Exportin 1 inhibitor
Use: | Treatment of multiple myeloma in combination with dexamethasone; treatment of diffuse large B-cell lymphoma (DLBCL) in patients who have received at least two prior therapies
Adult dose: | 60 mg orally once weekly for multiple myeloma; 100 mg orally twice weekly for DLBCL
Pediatric dose: | Safety and efficacy have not been established in pediatric patients
Side effects: | Nausea, vomiting, diarrhea, fatigue, anorexia, weight loss
Drug Class
Antineoplastic agent, Exportin 1 inhibitor
Uses & Indications
Treatment of multiple myeloma in combination with dexamethasone; treatment of diffuse large B-cell lymphoma (DLBCL) in patients who have received at least two prior therapies
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light
Manufacturer & Packaging
Manufacturer: Stemline Therapeutics, B.V.[Amsterdam;Netherlands, Netherlands
Package Size
32's (32 film Coated tablets)
Price & Supplier
Price in UAE: AED 106142.00
Dosage Information
Adult Dose
60 mg orally once weekly for multiple myeloma; 100 mg orally twice weekly for DLBCL
Pediatric Dose
Safety and efficacy have not been established in pediatric patients
Side Effects
Nausea, vomiting, diarrhea, fatigue, anorexia, weight loss, thrombocytopenia, neutropenia, anemia
Contraindications & Precautions
Hypersensitivity to selinexor or any component of the formulation; pregnancy (Category X)
Important Warnings
Risk of severe thrombocytopenia and neutropenia; monitor complete blood counts regularly; may cause fetal harm; use effective contraception during treatment and for at least 1 month after the last dose
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.