About SELINEXOR
Class: | Selective inhibitor of nuclear export (SINE)
Use: | Treatment of multiple myeloma in patients who have received at least four prior therapies, including a proteasome inhibitor and an immunomodulatory agent, and have demonstrated disease progression on the last therapy.
Adult dose: | 20 mg orally once weekly on days 1, 8, and 15 of a 28-day cycle; may be adjusted based on tolerance and side effects.
Pediatric dose: | Safety and efficacy have not been established in pediatric patien
Drug Class
Selective inhibitor of nuclear export (SINE)
Uses & Indications
Treatment of multiple myeloma in patients who have received at least four prior therapies, including a proteasome inhibitor and an immunomodulatory agent, and have demonstrated disease progression on the last therapy.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.
Manufacturer & Packaging
Manufacturer: Stemline Therapeutics, B.V.[Amsterdam;Netherlands, Netherlands
Package Size
12's (12 Tablets)
Price & Supplier
Price in UAE: AED 34787.50
Dosage Information
Adult Dose
20 mg orally once weekly on days 1, 8, and 15 of a 28-day cycle; may be adjusted based on tolerance and side effects.
Pediatric Dose
Safety and efficacy have not been established in pediatric patients; not recommended for use in this population.
Side Effects
Common side effects include nausea, vomiting, diarrhea, fatigue, decreased appetite, weight loss, and thrombocytopenia.
Contraindications & Precautions
Hypersensitivity to selinexor or any component of the formulation; pregnancy (Category X).
Important Warnings
Risk of severe thrombocytopenia, neutropenia, and anemia; monitor complete blood counts regularly. Risk of gastrointestinal toxicity; consider antiemetic prophylaxis. Use caution in patients with hepatic impairment.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.