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SELINEXOR – Uses, Dosage, and Brands in UAE

Brand Name: XPOVIO (Twice Weekly Pack)

Strength: 20 mg | Form: Tablets

Price in UAE: AED 139380.00

Available in UAE pharmacies

About SELINEXOR

Class: | Antineoplastic agent, Exportin 1 (XPO1) inhibitor Use: | Treatment of multiple myeloma in patients who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, two immunomodulatory agents, and an anti-CD38 monoclonal antibody. Adult dose: | 20 mg orally twice weekly on days 1 and 3 of a 28-day cycle. Pediatric dose: | Safety and efficacy have not been established in pediatric patients; not recommended for use in this popula

Drug Class

Antineoplastic agent, Exportin 1 (XPO1) inhibitor

Uses & Indications

Treatment of multiple myeloma in patients who have received at least four prior therapies and whose disease is refractory to at least two proteasome inhibitors, two immunomodulatory agents, and an anti-CD38 monoclonal antibody.

Storage Requirements

Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from moisture and light.

Manufacturer & Packaging

Manufacturer: KARYOPHARM THERAPEUTICS INC, United States of America

Package Size

32'S

Price & Supplier

Price in UAE: AED 139380.00

Dosage Information

Adult Dose

20 mg orally twice weekly on days 1 and 3 of a 28-day cycle.

Pediatric Dose

Safety and efficacy have not been established in pediatric patients; not recommended for use in this population.

Side Effects

Common side effects include nausea, vomiting, diarrhea, fatigue, decreased appetite, weight loss, thrombocytopenia, anemia, and neutropenia.

Contraindications & Precautions

Hypersensitivity to selinexor or any component of the formulation; pregnancy (Category X).

Important Warnings

Risk of severe thrombocytopenia, neutropenia, and anemia; monitor complete blood counts regularly. Risk of gastrointestinal toxicity; consider antiemetic prophylaxis. Use with caution in patients with hepatic impairment.

Other Brands & Strengths Available in UAE

Different brands and strengths of SELINEXOR available in UAE pharmacies:

NEXPOIO 20 mg Tablets NEXPOVIO 20 mg Tablets NEXPOVIO 20 mg Tablets NEXPOVIO 20 mg Tablets NEXPOVIO 20 mg Tablets NEXPOVIO 20 mg Tablets XPOVIO (Twice Weekly Pack) 20 mg Tablets

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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