About Phentolamine Mesilate (Mesylate)
Class: | Alpha-adrenergic antagonist
Use: | Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia in dental procedures; management of extravasation of vasopressors
Adult dose: | 5 mg to 10 mg IV/IM, may repeat every 5 to 15 minutes as needed; maximum dose varies based on clinical scenario
Pediatric dose: | Not established; use with caution and under specialist supervision
Side effects: | Hypotension, tachycardia, dizziness, flushing, nasal cong
Drug Class
Alpha-adrenergic antagonist
Uses & Indications
Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia in dental procedures; management of extravasation of vasopressors
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: NOVARTIS, Japan
Package Size
1mL Vial x 5
Price & Supplier
Price in UAE: AED 890.40
Dosage Information
Adult Dose
5 mg to 10 mg IV/IM, may repeat every 5 to 15 minutes as needed; maximum dose varies based on clinical scenario
Pediatric Dose
Not established; use with caution and under specialist supervision
Side Effects
Hypotension, tachycardia, dizziness, flushing, nasal congestion, gastrointestinal disturbances
Contraindications & Precautions
Hypersensitivity to phentolamine or any component of the formulation; patients with a history of coronary artery disease or myocardial infarction
Important Warnings
Use with caution in patients with cardiovascular disease; monitor blood pressure closely during administration; may cause significant hypotension; not recommended for use in patients with a history of hypersensitivity reactions to other alpha-adrenergic antagonists
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.