About Phentolamine Mesilate (Mesylate)
            
            Class: | Alpha-adrenergic antagonist  
Use: | Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia; management of erectile dysfunction in combination with other therapies  
Adult dose: | 5 mg to 10 mg IM or IV, may repeat every 1-2 hours as needed; maximum dose varies based on clinical situation  
Pediatric dose: | Safety and efficacy not established; use is generally not recommended in children  
Side effects: | Hypotension, tachycardia, dizziness, f
         
        
            
                
                
                    
                        Drug Class
                    
                    Alpha-adrenergic antagonist
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of hypertensive episodes associated with pheochromocytoma; reversal of local anesthesia; management of erectile dysfunction in combination with other therapies
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: TAGI Pharma, Inc., United States of America
                    
                    
                    Package Size
                    vial
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 2259.57
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        5 mg to 10 mg IM or IV, may repeat every 1-2 hours as needed; maximum dose varies based on clinical situation
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established; use is generally not recommended in children
                    
                 
                
                
                    
                        Side Effects
                    
                    Hypotension, tachycardia, dizziness, flushing, nasal congestion, diarrhea, and palpitations
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to phentolamine or any component of the formulation; patients with a history of myocardial infarction or coronary artery disease; patients with pheochromocytoma who are not adequately controlled
         
        
        
            
                Important Warnings
            
            Use with caution in patients with cardiovascular disease; may cause significant hypotension; monitor blood pressure closely during administration; potential for drug interactions with other antihypertensives and anesthetics
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.