About Phenytoin Sodium
Class: | Anticonvulsant, Hydantoin derivative
Use: | Management of generalized tonic-clonic seizures, complex partial seizures, and status epilepticus; also used for seizure prophylaxis in neurosurgery.
Adult dose: | Initial loading dose of 15-20 mg/kg IV, followed by maintenance doses of 300-400 mg/day in divided doses; adjust based on serum levels and clinical response.
Pediatric dose: | Loading dose of 15-20 mg/kg IV; maintenance dose of 5-10 mg/kg/day in divided doses, adjusted accordi
Drug Class
Anticonvulsant, Hydantoin derivative
Uses & Indications
Management of generalized tonic-clonic seizures, complex partial seizures, and status epilepticus; also used for seizure prophylaxis in neurosurgery.
Storage Requirements
Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze.
Manufacturer & Packaging
Manufacturer: Sterop Laboratories, BELGIUM
Package Size
5ml Ampoule x 100
Price & Supplier
Price in UAE: AED 748.00
Dosage Information
Adult Dose
Initial loading dose of 15-20 mg/kg IV, followed by maintenance doses of 300-400 mg/day in divided doses; adjust based on serum levels and clinical response.
Pediatric Dose
Loading dose of 15-20 mg/kg IV; maintenance dose of 5-10 mg/kg/day in divided doses, adjusted according to serum levels and clinical response.
Side Effects
Common side effects include dizziness, drowsiness, ataxia, nausea, vomiting, and gingival hyperplasia; may also cause rash and hypersensitivity reactions.
Contraindications & Precautions
Hypersensitivity to phenytoin or other hydantoins; history of acute hepatotoxicity; pregnancy (unless benefits outweigh risks); bradycardia or heart block.
Important Warnings
Monitor for signs of toxicity (e.g., nystagmus, ataxia, confusion); potential for serious skin reactions (Stevens-Johnson syndrome); caution in patients with liver disease; may interact with other medications affecting CYP450 enzymes.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.