About Linaclotide
            
            Class: | Guanylate cyclase-C agonist  
Use: | Treatment of irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC)  
Adult dose: | 72 mcg taken orally once daily, at least 30 minutes before the first meal of the day  
Pediatric dose: | Not approved for use in pediatric patients under 18 years of age  
Side effects: | Diarrhea, abdominal pain, flatulence, bloating, and headache  
Contraindications: | Known or suspected mechanical gastrointestinal obstruction; 
         
        
            
                
                
                    
                        Drug Class
                    
                    Guanylate cyclase-C agonist
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of irritable bowel syndrome with constipation (IBS-C) and chronic idiopathic constipation (CIC)
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature, 20°C to 25°C (68°F to 77°F); protect from moisture
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Ironwood Pharmaceuticals, CANADA
                    
                    
                    Package Size
                    30s
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 586.50
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        72 mcg taken orally once daily, at least 30 minutes before the first meal of the day
                    
                    
                        Pediatric Dose
                    
                    
                        Not approved for use in pediatric patients under 18 years of age
                    
                 
                
                
                    
                        Side Effects
                    
                    Diarrhea, abdominal pain, flatulence, bloating, and headache
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Known or suspected mechanical gastrointestinal obstruction; severe diarrhea; hypersensitivity to linaclotide or any component of the formulation
         
        
        
            
                Important Warnings
            
            Risk of dehydration due to diarrhea; not recommended for use in patients with a history of bowel obstruction; caution in patients with severe renal impairment or those taking medications that may exacerbate diarrhea
         
        
        
        
        
        
        
        
            
                Related Medicines in Same Category
            
            
                See also: Other Guanylate cyclase-C agonist medicines available in UAE pharmacies
            
            
            
                PLECANATIDE
            
            
         
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.