About Ezetimibe,Simvastatin
Class: | Antihyperlipidemic agent (combination of a cholesterol absorption inhibitor and a statin)
Use: | Used to lower cholesterol levels in patients with hyperlipidemia, to reduce the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease, and to manage dyslipidemia in conjunction with diet and exercise.
Adult dose: | Ezetimibe 10 mg and Simvastatin 10 mg to 20 mg once daily, taken in the evening. The maximum dose of Simvastatin is 40 mg per day.
Pediatric
Drug Class
Antihyperlipidemic agent (combination of a cholesterol absorption inhibitor and a statin)
Uses & Indications
Used to lower cholesterol levels in patients with hyperlipidemia, to reduce the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease, and to manage dyslipidemia in conjunction with diet and exercise.
Storage Requirements
Store at room temperature (20°C to 25°C or 68°F to 77°F) in a tightly closed container, protected from light and moisture.
Manufacturer & Packaging
Manufacturer: SUN PHARMACEUTICAL INDUSTRIES LTD., INDIA
Package Size
30s
Price & Supplier
Price in UAE: AED 43.00
Dosage Information
Adult Dose
Ezetimibe 10 mg and Simvastatin 10 mg to 20 mg once daily, taken in the evening. The maximum dose of Simvastatin is 40 mg per day.
Pediatric Dose
Not established for patients under 10 years; for patients aged 10-17 years, Simvastatin 10 mg to 20 mg once daily may be considered, with careful monitoring.
Side Effects
Common side effects include headache, abdominal pain, diarrhea, muscle pain, and elevated liver enzymes.
Contraindications & Precautions
Contraindicated in patients with active liver disease, unexplained persistent elevations of hepatic transaminase levels, and in those who are hypersensitive to any component of the formulation.
Important Warnings
Use with caution in patients with a history of liver disease, and monitor liver function tests periodically. Risk of myopathy and rhabdomyolysis, especially when used with other lipid-lowering therapies. Pregnant or breastfeeding women should avoid use.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.