About Ezetimibe,Simvastatin
Class: | Antihyperlipidemic agent (combination of a cholesterol absorption inhibitor and a statin)
Use: | Used to lower cholesterol levels in patients with hyperlipidemia, particularly to reduce LDL cholesterol and total cholesterol levels, and to decrease the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease.
Adult dose: | Ezetimibe 10 mg and Simvastatin 40 mg taken once daily, preferably in the evening.
Pediatric dose: | Not established for children un
Drug Class
Antihyperlipidemic agent (combination of a cholesterol absorption inhibitor and a statin)
Uses & Indications
Used to lower cholesterol levels in patients with hyperlipidemia, particularly to reduce LDL cholesterol and total cholesterol levels, and to decrease the risk of cardiovascular events in patients with atherosclerotic cardiovascular disease.
Storage Requirements
Store at room temperature, away from moisture and heat. Keep out of reach of children.
Manufacturer & Packaging
Manufacturer: TAD Pharma GmbH, Germany
Package Size
28s
Price & Supplier
Price in UAE: AED 143.50
Dosage Information
Adult Dose
Ezetimibe 10 mg and Simvastatin 40 mg taken once daily, preferably in the evening.
Pediatric Dose
Not established for children under 10 years; for children 10-17 years, Ezetimibe 10 mg and Simvastatin 10-40 mg may be used, but dosing should be individualized based on LDL levels and tolerability.
Side Effects
Common side effects include headache, abdominal pain, diarrhea, muscle pain, and elevated liver enzymes.
Contraindications & Precautions
Contraindicated in patients with active liver disease, unexplained persistent elevations of serum transaminases, and in those who are pregnant or breastfeeding.
Important Warnings
Use with caution in patients with a history of liver disease, and monitor liver function tests periodically. Increased risk of myopathy and rhabdomyolysis, especially when used with other statins or certain medications that affect liver metabolism.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.