About Vemurafenib
            
            Class: | BRAF inhibitor  
Use: | Treatment of unresectable or metastatic melanoma with BRAF V600E mutation  
Adult dose: | 960 mg orally twice daily (240 mg tablets, taken as four tablets)  
Pediatric dose: | Safety and efficacy not established in pediatric patients  
Side effects: | Rash, arthralgia, fatigue, photosensitivity, nausea, diarrhea, liver enzyme elevations  
Contraindications: | Hypersensitivity to vemurafenib or any component of the formulation; concomitant use with strong CYP3A in
         
        
            
                
                
                    
                        Drug Class
                    
                    BRAF inhibitor
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of unresectable or metastatic melanoma with BRAF V600E mutation
                 
                
                
                    
                        Storage Requirements
                    
                    Store at 20°C to 25°C (68°F to 77°F); protect from moisture and light
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: F. Hoffmann La Roche, ITALY
                    
                    
                    Package Size
                    56's (7 Blisters x 8)
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 13182.70
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        960 mg orally twice daily (240 mg tablets, taken as four tablets)
                    
                    
                        Pediatric Dose
                    
                    
                        Safety and efficacy not established in pediatric patients
                    
                 
                
                
                    
                        Side Effects
                    
                    Rash, arthralgia, fatigue, photosensitivity, nausea, diarrhea, liver enzyme elevations
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Hypersensitivity to vemurafenib or any component of the formulation; concomitant use with strong CYP3A inhibitors
         
        
        
            
                Important Warnings
            
            Risk of new malignancies (non-melanoma skin cancers), hepatotoxicity, QT prolongation, and serious skin reactions; monitor liver function tests regularly during treatment
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.