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Arsenic Trioxide – Uses, Dosage, and Brands in UAE

Brand Name: ARSENIC TRIOXIDE
Strength: 1 mg/ml | Form: Solution For Injection
Price in UAE: AED 2452.80
Available in UAE pharmacies

About Arsenic Trioxide

Class: | Antineoplastic agent, Chemotherapy agent Use: | Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy Adult dose: | Initial dose of 0.15 mg/kg IV daily for 5 days, followed by 0.1 mg/kg IV daily for 5 days in subsequent cycles; may be adjusted based on clinical response and tolerability Pediatric dose: | Safety and efficacy not established; use is generally not recommended in pediatric population

Drug Class

Antineoplastic agent, Chemotherapy agent

Uses & Indications

Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy

Storage Requirements

Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze

Manufacturer & Packaging

Manufacturer: JUNO Pharmaceuticals PTY LTD., AUSTRALIA

Package Size

10ml vial x 10

Price & Supplier

Price in UAE: AED 2452.80

Dosage Information

Adult Dose

Initial dose of 0.15 mg/kg IV daily for 5 days, followed by 0.1 mg/kg IV daily for 5 days in subsequent cycles; may be adjusted based on clinical response and tolerability

Pediatric Dose

Safety and efficacy not established; use is generally not recommended in pediatric populations

Side Effects

Common side effects include fatigue, nausea, vomiting, diarrhea, headache, and peripheral neuropathy; serious side effects may include QT prolongation, differentiation syndrome, and liver enzyme elevations

Contraindications & Precautions

Known hypersensitivity to arsenic trioxide or any component of the formulation; caution in patients with pre-existing cardiac conditions due to risk of QT prolongation

Important Warnings

Monitor for signs of differentiation syndrome; perform regular ECGs to assess for QT prolongation; use caution in patients with renal impairment; pregnancy category D; may cause fetal harm

Other Brands & Strengths Available in UAE

Different brands and strengths of Arsenic Trioxide available in UAE pharmacies:

ARSENIC TRIOXIDE 1 mg/ml Preservative-Free Solution For Infusion ARSENIC TRIOXIDE 1 mg/ml Solution For Injection ARSENIC TRIOXIDE 1 mg/ml Solution For Injection ATOYI 10 mg/10ml Solution For Injection PHENASEN 1 mg/ml Solution For Injection TRISENOX 1 mg/ml Solution For Injection

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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