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Arsenic Trioxide – Uses, Dosage, and Brands in UAE

Brand Name: PHENASEN
Strength: 1 mg/ml | Form: Solution For Injection
Price in UAE: AED 21620.00
Available in UAE pharmacies

About Arsenic Trioxide

Class: | Antineoplastic agent, specifically a differentiation agent Use: | Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy Adult dose: | Initial dose of 0.15 mg/kg/day as a continuous intravenous infusion for 5 days, followed by a 2-day break; this cycle can be repeated until remission is achieved or toxicity occurs Pediatric dose: | Safety and efficacy have not been established in pediatric patient

Drug Class

Antineoplastic agent, specifically a differentiation agent

Uses & Indications

Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy

Storage Requirements

Store at room temperature (20°C to 25°C or 68°F to 77°F); protect from light and do not freeze; once diluted, use within 24 hours if stored at room temperature

Manufacturer & Packaging

Manufacturer: Phebra Pty Ltd, AUSTRALIA

Package Size

10ml Ampoule x 10's

Price & Supplier

Price in UAE: AED 21620.00

Dosage Information

Adult Dose

Initial dose of 0.15 mg/kg/day as a continuous intravenous infusion for 5 days, followed by a 2-day break; this cycle can be repeated until remission is achieved or toxicity occurs

Pediatric Dose

Safety and efficacy have not been established in pediatric patients; dosing should be determined by a healthcare professional based on individual circumstances

Side Effects

Common side effects include fatigue, headache, nausea, vomiting, diarrhea, and peripheral edema; more serious effects can include QT prolongation, differentiation syndrome, and liver enzyme elevation

Contraindications & Precautions

Hypersensitivity to arsenic trioxide or any component of the formulation; caution in patients with pre-existing cardiac conditions due to the risk of QT prolongation

Important Warnings

Monitor for signs of differentiation syndrome, which can be life-threatening; regular ECG monitoring is recommended due to the risk of QT prolongation; use caution in patients with hepatic impairment

Other Brands & Strengths Available in UAE

Different brands and strengths of Arsenic Trioxide available in UAE pharmacies:

ARSENIC TRIOXIDE 1 mg/ml Preservative-Free Solution For Infusion ARSENIC TRIOXIDE 1 mg/ml Solution For Injection ARSENIC TRIOXIDE 1 mg/ml Solution For Injection ATOYI 10 mg/10ml Solution For Injection PHENASEN 1 mg/ml Solution For Injection TRISENOX 1 mg/ml Solution For Injection

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

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