Arsenic Trioxide (ATOYI) – Uses, Dosage & Brands in UAE

About Arsenic Trioxide

Class: | Antineoplastic agent, specifically a chemotherapy drug used in the treatment of certain types of leukemia Use: | Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy Adult dose: | 0.15 mg/kg IV daily for 5 days, followed by a 2-day break; this cycle can be repeated until complete remission is achieved, typically for a total of 2-4 cycles Pediatric dose: | Safety and efficacy have not been establ

Drug Class

Antineoplastic agent, specifically a chemotherapy drug used in the treatment of certain types of leukemia

Uses & Indications

Treatment of acute promyelocytic leukemia (APL) in patients who are refractory to or have relapsed after retinoid and anthracycline therapy

Storage Requirements

Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze

Manufacturer & Packaging

Manufacturer: Amneal Pharmaceuticals of New York, United States of America

Package Size

10 Glass Vials (10ml)

Price & Supplier

Price in UAE: AED 25763.00

Dosage Information

Adult Dose

0.15 mg/kg IV daily for 5 days, followed by a 2-day break; this cycle can be repeated until complete remission is achieved, typically for a total of 2-4 cycles

Pediatric Dose

Safety and efficacy have not been established in pediatric patients; dosing should be determined by a specialist

Side Effects

Common side effects include fatigue, nausea, vomiting, headache, fever, and peripheral neuropathy; serious side effects may include QT prolongation, differentiation syndrome, and cardiac toxicity

Important Warnings

Monitor for signs of differentiation syndrome, which can be life-threatening; regular ECG monitoring is recommended due to the risk of QT prolongation; ensure electrolyte levels (especially potassium and magnesium) are normal prior to and during treatment

Medical Disclaimer

This information is for educational purposes only and should not replace professional medical advice. Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. The information presented here is specific to medicines available in UAE pharmacies and is regularly updated to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.

Arsenic Trioxide – Uses, Dosage, and Brands in UAE