About Methotrexate
Class: | Antimetabolite, Disease-modifying antirheumatic drug (DMARD)
Use: | Treatment of various cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy
Adult dose: | Varies by indication; typically, for rheumatoid arthritis, 7.5 to 25 mg once weekly; for cancer, doses can range from 10 to 30 mg/m² weekly or higher depending on the protocol
Pediatric dose: | Varies by indication; for acute lymphoblastic leukemia, 1-5 mg/m² wee
Drug Class
Antimetabolite, Disease-modifying antirheumatic drug (DMARD)
Uses & Indications
Treatment of various cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy
Storage Requirements
Store at 20-25°C (68-77°F); protect from light; do not freeze
Manufacturer & Packaging
Manufacturer: Ebewe Pharma Ges. m.b.H MFG. KG, AUSTRIA
Package Size
1ml Pre-filled Syringe
Price & Supplier
Price in UAE: AED 107.50
Dosage Information
Adult Dose
Varies by indication; typically, for rheumatoid arthritis, 7.5 to 25 mg once weekly; for cancer, doses can range from 10 to 30 mg/m² weekly or higher depending on the protocol
Pediatric Dose
Varies by indication; for acute lymphoblastic leukemia, 1-5 mg/m² weekly; dosing should be determined by a pediatric oncologist
Side Effects
Nausea, vomiting, diarrhea, stomatitis, fatigue, liver enzyme elevation, bone marrow suppression, increased risk of infections
Contraindications & Precautions
Pregnancy, breastfeeding, severe liver disease, active infections, blood dyscrasias, hypersensitivity to methotrexate or any component of the formulation
Important Warnings
Risk of severe toxicity, including hepatotoxicity, pulmonary toxicity, and myelosuppression; monitor liver function tests and complete blood counts regularly; avoid use with NSAIDs and live vaccines during treatment
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.