About Methotrexate
Class: | Antimetabolite, Disease-modifying antirheumatic drug (DMARD)
Use: | Treatment of certain cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy
Adult dose: | Varies by condition; for rheumatoid arthritis, typically 7.5 to 25 mg once weekly; for cancer, doses can range from 15 mg/m² to 30 mg/m² weekly or higher depending on the protocol
Pediatric dose: | For juvenile idiopathic arthritis, typically 10 mg/m² once weekly
Drug Class
Antimetabolite, Disease-modifying antirheumatic drug (DMARD)
Uses & Indications
Treatment of certain cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy
Storage Requirements
Store at room temperature (20-25°C or 68-77°F), protect from light, keep out of reach of children
Manufacturer & Packaging
Manufacturer: Ebewe Pharma, AUSTRIA
Package Size
50's
Price & Supplier
Price in UAE: AED 96.00
Dosage Information
Adult Dose
Varies by condition; for rheumatoid arthritis, typically 7.5 to 25 mg once weekly; for cancer, doses can range from 15 mg/m² to 30 mg/m² weekly or higher depending on the protocol
Pediatric Dose
For juvenile idiopathic arthritis, typically 10 mg/m² once weekly; dosing may vary based on specific condition and physician recommendation
Side Effects
Nausea, vomiting, diarrhea, mouth sores, fatigue, liver enzyme elevation, bone marrow suppression, increased risk of infection
Contraindications & Precautions
Hypersensitivity to methotrexate, pregnancy (category X), breastfeeding, active infections, severe liver disease, renal impairment
Important Warnings
Risk of severe toxicity, including hepatotoxicity, pulmonary toxicity, and myelosuppression; monitor liver function and blood counts regularly; avoid use with alcohol and certain medications that may increase toxicity
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.