About Methotrexate
            
            Class: | Antimetabolite, Disease-modifying antirheumatic drug (DMARD)  
Use: | Treatment of certain cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy  
Adult dose: | Varies based on indication; typically 7.5 mg to 25 mg once weekly for rheumatoid arthritis; higher doses for cancer treatment as determined by oncologist  
Pediatric dose: | Varies based on indication; generally 0.3 to 1 mg/kg/week for juvenile idiopathic arthritis
         
        
            
                
                
                    
                        Drug Class
                    
                    Antimetabolite, Disease-modifying antirheumatic drug (DMARD)
                 
                
                
                    
                        Uses & Indications
                    
                    Treatment of certain cancers (e.g., leukemia, lymphoma), autoimmune diseases (e.g., rheumatoid arthritis, psoriasis), and ectopic pregnancy
                 
                
                
                    
                        Storage Requirements
                    
                    Store at room temperature (20-25°C or 68-77°F); protect from light; do not freeze
                 
                
                
                    
                        Manufacturer & Packaging
                    
                    
                        Manufacturer: Therakind (Europe) Limited, Ireland
                    
                    
                    Package Size
                    60ml Amber Glass Bottle
                    
                    
                    Price & Supplier
                    
                        Price in UAE: AED 683.00
                    
                    
                 
             
            
                
                
                    
                        Dosage Information
                    
                    
                        Adult Dose
                    
                    
                        Varies based on indication; typically 7.5 mg to 25 mg once weekly for rheumatoid arthritis; higher doses for cancer treatment as determined by oncologist
                    
                    
                        Pediatric Dose
                    
                    
                        Varies based on indication; generally 0.3 to 1 mg/kg/week for juvenile idiopathic arthritis; specific dosing should be determined by a pediatric specialist
                    
                 
                
                
                    
                        Side Effects
                    
                    Nausea, vomiting, diarrhea, mouth sores, fatigue, liver enzyme elevation, bone marrow suppression, increased risk of infections
                 
             
         
        
        
            
                Contraindications & Precautions
            
            Pregnancy, breastfeeding, severe liver disease, active infections, blood disorders (e.g., leukopenia, thrombocytopenia), hypersensitivity to methotrexate
         
        
        
            
                Important Warnings
            
            Risk of severe toxicity, including hepatotoxicity, pulmonary toxicity, and myelosuppression; monitor liver function and blood counts regularly; avoid use with NSAIDs and other nephrotoxic agents; contraindicated in patients with active infections or significant renal impairment
         
        
        
        
        
        
        
        
        
        
        
            
                Medical Disclaimer
            
            
                This information is for educational purposes only and should not replace professional medical advice. 
                Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication. 
                The information presented here is specific to medicines available in UAE pharmacies and is regularly updated 
                to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.