About ETEPLIRSEN
Class: | Antisense oligonucleotide
Use: | Eteplirsen is indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 51 skipping.
Adult dose: | Not applicable, as Eteplirsen is specifically indicated for pediatric use.
Pediatric dose: | The recommended dose is 30 mg/kg administered once weekly as an intravenous infusion over 35 to 60 minutes.
Side effects: | Common side effects include balance disorder, vomiti
Drug Class
Antisense oligonucleotide
Uses & Indications
Eteplirsen is indicated for the treatment of Duchenne muscular dystrophy (DMD) in patients who have a confirmed mutation of the DMD gene that is amenable to exon 51 skipping.
Storage Requirements
Store Eteplirsen in a refrigerator at 2°C to 8°C (36°F to 46°F). Do not freeze. Protect from light and store in the original carton until use.
Manufacturer & Packaging
Manufacturer: Sarepta Therapeutics Inc., United States of America
Package Size
1 vial
Price & Supplier
Price in UAE: AED 33649.35
Dosage Information
Adult Dose
Not applicable, as Eteplirsen is specifically indicated for pediatric use.
Pediatric Dose
The recommended dose is 30 mg/kg administered once weekly as an intravenous infusion over 35 to 60 minutes.
Side Effects
Common side effects include balance disorder, vomiting, and contact dermatitis.
Contraindications & Precautions
There are no known contraindications for Eteplirsen; however, caution is advised in patients with known hypersensitivity to the drug or any of its components.
Important Warnings
Monitor renal function as Eteplirsen may increase the risk of renal toxicity. Use caution in patients with pre-existing renal impairment. Regular monitoring of urine dipstick and serum creatinine is recommended.
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.