About Tofersen
Class: | Antisense oligonucleotide
Use: | Treatment of amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations
Adult dose: | 100 mg administered as a subcutaneous injection once weekly
Pediatric dose: | Safety and efficacy not established in pediatric patients
Side effects: | Injection site reactions, headache, nausea, fatigue, diarrhea
Contraindications: | Hypersensitivity to tofersen or any component of the formulation
Storage: | Store in the ref
Drug Class
Antisense oligonucleotide
Uses & Indications
Treatment of amyotrophic lateral sclerosis (ALS) associated with superoxide dismutase 1 (SOD1) mutations
Storage Requirements
Store in the refrigerator at 2°C to 8°C (36°F to 46°F); do not freeze; protect from light
Manufacturer & Packaging
Manufacturer: Biogen Netherlands B.V. {Badhoevedorp; Netherlands}, Netherlands
Package Size
1's Glass Vial (15 ml)
Price & Supplier
Price in UAE: AED 118985.00
Dosage Information
Adult Dose
100 mg administered as a subcutaneous injection once weekly
Pediatric Dose
Safety and efficacy not established in pediatric patients
Side Effects
Injection site reactions, headache, nausea, fatigue, diarrhea
Contraindications & Precautions
Hypersensitivity to tofersen or any component of the formulation
Important Warnings
Risk of serious hypersensitivity reactions; monitor for signs of anaphylaxis; not recommended for use in patients with known hypersensitivity to the drug
Medical Disclaimer
This information is for educational purposes only and should not replace professional medical advice.
Always consult with a licensed healthcare provider or pharmacist in the UAE before taking any medication.
The information presented here is specific to medicines available in UAE pharmacies and is regularly updated
to ensure accuracy for patients and healthcare professionals in the United Arab Emirates.